Induction of Oxidative Stress in Trypanosoma brucei by the Antitrypanosomal Dihydroquinoline OSU-40

Dihydroquinoline derivative OSU-40 (1-benzyl-1,2-dihydro-2,2,4-trimethylquinolin-6-yl acetate) is selectively potent against Trypanosma brucei rhodesiense in vitro (50% inhibitory concentration [IC(50)], 14 nM; selectivity index, 1,700) and has been proposed to cause the formation of reactive oxygen...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: He, Shanshan, Dayton, Alex, Kuppusamy, Periannan, Werbovetz, Karl A., Drew, Mark E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
Предметы:
Mechanisms of Action: Physiological Effects
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346584/
https://ncbi.nlm.nih.gov/pubmed/22314522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06386-11
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы