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Development of a specific ELISA to measure BACE1 levels in human tissues

The aspartyl protease BACE1 is the rate limiting enzyme in the synthesis of amyloid beta, which accumulation in the human brain is a hallmark of Alzheimer’s disease (AD). BACE1 has been proposed as a surrogate marker of AD; however, very few BACE1 immunoassays have been reported. In the present stud...

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Autors principals: Gonzales, Amanda, Decourt, Boris, Walker, Aaron, Condjella, Rachel, Nural, Hikmet, Sabbagh, Marwan N.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346260/
https://ncbi.nlm.nih.gov/pubmed/21889954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2011.08.030
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