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Development of a specific ELISA to measure BACE1 levels in human tissues
The aspartyl protease BACE1 is the rate limiting enzyme in the synthesis of amyloid beta, which accumulation in the human brain is a hallmark of Alzheimer’s disease (AD). BACE1 has been proposed as a surrogate marker of AD; however, very few BACE1 immunoassays have been reported. In the present stud...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3346260/ https://ncbi.nlm.nih.gov/pubmed/21889954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2011.08.030 |
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