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Isolation of cloned Moloney murine leukemia virus reverse transcriptase lacking ribonuclease H activity.

Retroviral reverse transcriptase possesses DNA polymerase and ribonuclease H (RNase H) activity within a single polypeptide. Chemical or proteolytic treatment of reverse transcriptase has been used in the past to produce enzyme that is missing DNA polymerase activity and retains RNase H activity. It...

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Udgivet i:Nucleic Acids Res
Principais autores: Kotewicz, M L, Sampson, C M, D'Alessio, J M, Gerard, G F
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1988
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334625/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2448747/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.1.265
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