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Isolation of cloned Moloney murine leukemia virus reverse transcriptase lacking ribonuclease H activity.

Retroviral reverse transcriptase possesses DNA polymerase and ribonuclease H (RNase H) activity within a single polypeptide. Chemical or proteolytic treatment of reverse transcriptase has been used in the past to produce enzyme that is missing DNA polymerase activity and retains RNase H activity. It...

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Detalhes bibliográficos
Main Authors: Kotewicz, M L, Sampson, C M, D'Alessio, J M, Gerard, G F
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC334625/
https://ncbi.nlm.nih.gov/pubmed/2448747
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