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Reconstitution of Glucosylceramide Flip-Flop across Endoplasmic Reticulum: IMPLICATIONS FOR MECHANISM OF GLYCOSPHINGOLIPID BIOSYNTHESIS

Most glycosphingolipids are synthesized by the sequential addition of monosaccharides to glucosylceramide (GlcCer) in the lumen of the Golgi apparatus. Because GlcCer is synthesized on the cytoplasmic face of Golgi membranes, it must be flipped to the non-cytoplasmic face by a lipid flippase in orde...

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Main Authors: Chalat, Madhavan, Menon, Indu, Turan, Zeynep, Menon, Anant K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346150/
https://ncbi.nlm.nih.gov/pubmed/22427661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.343038
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