Endocannabinoids Stimulate Human Melanogenesis via Type-1 Cannabinoid Receptor

We show that a fully functional endocannabinoid system is present in primary human melanocytes (normal human epidermal melanocyte cells), including anandamide (AEA), 2-arachidonoylglycerol, the respective target receptors (CB(1), CB(2), and TRPV1), and their metabolic enzymes. We also show that at h...

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Autors principals: Pucci, Mariangela, Pasquariello, Nicoletta, Battista, Natalia, Di Tommaso, Monia, Rapino, Cinzia, Fezza, Filomena, Zuccolo, Michela, Jourdain, Roland, Finazzi Agrò, Alessandro, Breton, Lionel, Maccarrone, Mauro
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Lipids
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346111/
https://ncbi.nlm.nih.gov/pubmed/22431736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.314880
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