Functional and Structural Analysis of the Siderophore Synthetase AsbB through Reconstitution of the Petrobactin Biosynthetic Pathway from Bacillus anthracis

Petrobactin, a mixed catechol-carboxylate siderophore, is required for full virulence of Bacillus anthracis, the causative agent of anthrax. The asbABCDEF operon encodes the biosynthetic machinery for this secondary metabolite. Here, we show that the function of five gene products encoded by the asb...

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Detalhes bibliográficos
Main Authors: Nusca, Tyler D., Kim, Youngchang, Maltseva, Natalia, Lee, Jung Yeop, Eschenfeldt, William, Stols, Lucy, Schofield, Michael M., Scaglione, Jamie B., Dixon, Shandee D., Oves-Costales, Daniel, Challis, Gregory L., Hanna, Philip C., Pfleger, Brian F., Joachimiak, Andrzej, Sherman, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346087/
https://ncbi.nlm.nih.gov/pubmed/22408253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359349
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