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Brain slices from glutaminase-deficient mice metabolize less glutamine: a cellular metabolomic study with carbon 13 NMR
In the brain, glutaminase is considered to have a key role in the provision of glutamate, a major excitatory neurotransmitter. Brain slices obtained from wild-type (control) and glutaminase-deficient (GLS1+/−) mice were incubated without glucose and with 5 or 1 mmol/L [3-(13)C]glutamine as substrate...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345920/ https://ncbi.nlm.nih.gov/pubmed/22373647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.22 |
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