Guanine nucleotide-binding protein Gαi2: a new partner of claudin-5 that regulates tight junction integrity in human brain endothelial cells

The blood–brain barrier (BBB) selectively controls the exchanges between the blood and the brain: it is formed by tight junctions (TJs) between adjacent microvascular endothelial cells. The transmembrane protein claudin-5 is known as a key TJ protein at the BBB, although, the molecular mechanisms by...

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Bibliografiske detaljer
Main Authors: Luissint, Anny-Claude, Federici, Christian, Guillonneau, François, Chrétien, Fabrice, Camoin, Luc, Glacial, Fabienne, Ganeshamoorthy, Kayathiri, Couraud, Pierre-Olivier
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345908/
https://ncbi.nlm.nih.gov/pubmed/22333621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.202
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