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Controlled Systemic Delivery by Polymeric Implants Enhances Tissue and Plasma Curcumin Levels Compared with Oral Administration

Curcumin possess potent anti-inflammatory and anti-proliferative activities but with poor biopharmaceutical attributes. To overcome these limitations, curcumin implants were developed and tissue (plasma, brain and liver) curcumin concentrations were measured in female ACI rats for 3 months. Biologic...

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Detalhes bibliográficos
Main Authors: Bansal, Shyam S., Kausar, Hina, Vadhanam, Manicka V., Ravoori, Srivani, Gupta, Ramesh C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345811/
https://ncbi.nlm.nih.gov/pubmed/22227368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2011.12.009
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