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NMR observation of individual molecules of hydration water bound to DNA duplexes: direct evidence for a spine of hydration water present in aqueous solution.

The residence times of individual hydration water molecules in the major and minor grooves of DNA were measured by nuclear magnetic resonance (NMR) spectroscopy in aqueous solutions of d-(CGCGAATTCGCG)2 and d-(AAAAATTTTT)2. The experimental observations were nuclear Overhauser effects (NOE) between...

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Autores principales: Liepinsh, E, Otting, G, Wüthrich, K
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC334570/
https://ncbi.nlm.nih.gov/pubmed/1480475
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