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NMR observation of individual molecules of hydration water bound to DNA duplexes: direct evidence for a spine of hydration water present in aqueous solution.

The residence times of individual hydration water molecules in the major and minor grooves of DNA were measured by nuclear magnetic resonance (NMR) spectroscopy in aqueous solutions of d-(CGCGAATTCGCG)2 and d-(AAAAATTTTT)2. The experimental observations were nuclear Overhauser effects (NOE) between...

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Detalhes bibliográficos
Main Authors: Liepinsh, E, Otting, G, Wüthrich, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC334570/
https://ncbi.nlm.nih.gov/pubmed/1480475
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