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Adverse Interactions between Antifungal Azoles and Vincristine: Review and Analysis of Cases
Triazole and imidazole antifungal agents inhibit metabolism of vincristine, leading to excess vinca alkaloid exposure and severe neurotoxicity. Recent reports of debilitating interactions between vincristine and itraconazole, as well as posaconazole, voriconazole and ketoconazole underscore the need...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345292/ https://ncbi.nlm.nih.gov/pubmed/22126626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1439-0507.2011.02158.x |
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