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UVB and pro-inflammatory cytokines synergistically activate TNF-α production in keratinocytes through enhanced gene transcription

Ultraviolet B (UVB) irradiation potently induces cytokines in the skin, including interleukin-1α (IL-1α) and tumor necrosis factor-α (TNF-α). The mechanism for TNF-α induction in UVB-irradiated keratinocytes is not clear. In the current study, we explored the effects of UVB and cytokines, alone or i...

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Bibliographische Detailangaben
Hauptverfasser: Bashir, Muhammad M., Sharma, Meena R., Werth, Victoria P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345265/
https://ncbi.nlm.nih.gov/pubmed/19005488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.332
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