MAPK/ERK Signaling in Osteosarcomas, Ewing Sarcomas and Chondrosarcomas: Therapeutic Implications and Future Directions

The introduction of cytotoxic chemotherapeutic drugs in the 1970's improved the survival rate of patients with bone sarcomas and allowed limb salvage surgeries. However, since the turn of the century, survival data has plateaued for a subset of metastatic, nonresponding osteo, and/or Ewing sarc...

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Bibliografiske detaljer
Main Authors: Chandhanayingyong, Chandhanarat, Kim, Yuhree, Staples, J. Robert, Hahn, Cody, Lee, Francis Youngin
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345255/
https://ncbi.nlm.nih.gov/pubmed/22577336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/404810
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