Toxicity and Efficacy of the Acetylcholinesterase (AChe) Inhibitor Donepezil in Childhood Brain Tumor Survivors: A Pilot Study

BACKGROUND: Neurocognitive deficits are a recognized late effect of curative brain tumor therapy. We evaluated the feasibility, tolerance, and impact of a pilot pharmacologic intervention with the acetylcholinesterase (AChe) inhibitor, donepezil, in pediatric brain tumor (BT) survivors at risk for n...

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Main Authors: Castellino, Sharon M., Tooze, Janet A., Flowers, Lynn, Hill, Debbie F., McMullen, Kevin P., Shaw, Edward G., Parsons, Susan K.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345166/
https://ncbi.nlm.nih.gov/pubmed/22238217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24078
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