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Membrane binding of Escherichia coli RNase E catalytic domain stabilizes protein structure and increases RNA substrate affinity

RNase E plays an essential role in RNA processing and decay and tethers to the cytoplasmic membrane in Escherichia coli; however, the function of this membrane–protein interaction has remained unclear. Here, we establish a mechanistic role for the RNase E–membrane interaction. The reconstituted high...

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Detalhes bibliográficos
Main Authors: Murashko, Oleg N., Kaberdin, Vladimir R., Lin-Chao, Sue
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344982/
https://ncbi.nlm.nih.gov/pubmed/22509045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120181109
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