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Differential Evolutionary Wiring of the Tyrosine Kinase Btk

BACKGROUND: A central question within biology is how intracellular signaling pathways are maintained throughout evolution. Btk29A is considered to be the fly-homolog of the mammalian Bruton’s tyrosine kinase (Btk), which is a non-receptor tyrosine-kinase of the Tec-family. In mammalian cells, there...

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Detalhes bibliográficos
Main Authors: Nawaz, Hossain M., Kylsten, Per, Hamada, Noriko, Yamamoto, Daisuke, Smith, C. I. Edvard, Lindvall, Jessica M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344829/
https://ncbi.nlm.nih.gov/pubmed/22574122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035640
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