The Threonine Protease Activity of Testes-Specific Protease 50 (TSP50) Is Essential for Its Function in Cell Proliferation

BACKGROUND: Testes-specific protease 50 (TSP50), a newly discovered threonine enzyme, has similar amino acid sequences and enzymatic structures to those of many serine proteases. It may be an oncogene. TSP50 is up-regulated in breast cancer epithelial cells, and ectopic expression of TSP50 in TSP50-...

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Autors principals: Li, Yu-Yin, Bao, Yong-Li, Song, Zhen-Bo, Sun, Lu-Guo, Wu, Ping, Zhang, Yu, Fan, Cong, Huang, Yan-Xin, Wu, Yin, Yu, Chun-Lei, Sun, Ying, Zheng, Li-Hua, Wang, Guan-Nan, Li, Yu-Xin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344824/
https://ncbi.nlm.nih.gov/pubmed/22574111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035030
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