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Rhinacanthus nasutus Extracts Prevent Glutamate and Amyloid-β Neurotoxicity in HT-22 Mouse Hippocampal Cells: Possible Active Compounds Include Lupeol, Stigmasterol and β-Sitosterol

The Herb Rhinacanthus nasutus (L.) Kurz, which is native to Thailand and Southeast Asia, has become known for its antioxidant properties. Neuronal loss in a number of diseases including Alzheimer’s disease is thought to result, in part, from oxidative stress. Glutamate causes cell death in the mouse...

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Detalhes bibliográficos
Main Authors: Brimson, James M., Brimson, Sirikalaya J., Brimson, Christopher A., Rakkhitawatthana, Varaporn, Tencomnao, Tewin
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344267/
https://ncbi.nlm.nih.gov/pubmed/22606031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13045074
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