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Mutation of the casein kinase II phosphorylation site abolishes the anti-proliferative activity of p53.
The p53 tumour suppressor protein is phosphorylated by several protein kinases, including casein kinase II. In order to understand the functional significance of phosphorylation by casein kinase II, we have introduced mutations at serine 386 in mouse p53, the residue phosphorylated by this kinase, a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1992
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC334387/ https://ncbi.nlm.nih.gov/pubmed/1454521 |
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