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Canonical type I interferon signaling in SIV infected macrophages is disrupted by astrocyte-secreted CCL2
HIV associated neurological disorders (HAND) are a mounting problem despite the advent of highly active antiretroviral therapy. To address mechanisms of HAND we used an SIV pigtailed macaque model to study innate immune responses in brain that suppress viral replication during acute infection. We pr...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3343693/ https://ncbi.nlm.nih.gov/pubmed/22407919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103024 |
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