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Preferential CTL targeting of Gag is associated with relative viral control in long-term surviving HIV-1 infected former plasma donors from China

It is generally believed that CD8(+) cytotoxic T lymphocytes (CTLs) play a critical role in limiting the replication of human immunodeficiency virus type 1 (HIV-1) and in determining the outcome of the infection, and this effect may partly depend on which HIV product is preferentially targeted. To a...

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Détails bibliographiques
Auteurs principaux: Jia, Mingming, Hong, Kunxue, Chen, Jianping, Ruan, Yuhua, Wang, Zhe, Su, Bing, Ren, Guoliang, Zhang, Xiaoqing, Liu, Zhen, Zhao, Quanbi, Li, Dan, Peng, Hong, Altfeld, Marcus, Walker, Bruce D, Yu, Xu G, Shao, Yiming
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343654/
https://ncbi.nlm.nih.gov/pubmed/22290423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.19
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