Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice

Mitochondria are dynamic subcellular organelles that convert nutrient intermediates into readily available energy equivalents. Optimal mitochondrial function is ensured by a highly evolved quality control system, coordinated by protein machinery that regulates a process of continual fusion and fissi...

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Detalhes bibliográficos
Main Authors: Quirós, Pedro M, Ramsay, Andrew J, Sala, David, Fernández-Vizarra, Erika, Rodríguez, Francisco, Peinado, Juan R, Fernández-García, Maria Soledad, Vega, José A, Enríquez, José A, Zorzano, Antonio, López-Otín, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343468/
https://ncbi.nlm.nih.gov/pubmed/22433842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.70
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