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Cyclin D2 in the basal process of neural progenitors is linked to non-equivalent cell fates

Asymmetric cell division plays an indispensable role during corticogenesis for producing new neurons while maintaining a self-renewing pool of apical progenitors. The cellular and molecular determinants favouring asymmetric division are not completely understood. Here, we identify a novel mechanism...

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Detalhes bibliográficos
Main Authors: Tsunekawa, Yuji, Britto, Joanne M, Takahashi, Masanori, Polleux, Franck, Tan, Seong-Seng, Osumi, Noriko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343330/
https://ncbi.nlm.nih.gov/pubmed/22395070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.43
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