Contribution of Fibroblast and Mast Cell (Afferent) and Tumor (Efferent) IL-6 Effects within the Tumor Microenvironment

Hyperactive inflammatory responses following cancer initiation have led to cancer being described as a ‘wound that never heals’. These inflammatory responses elicit signals via NFκB leading to IL-6 production, and IL-6 in turn has been shown to induce epithelial to mesenchymal transition in breast c...

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Bibliographic Details
Main Authors: Hugo, Honor J., Lebret, Stephanie, Tomaskovic-Crook, Eva, Ahmed, Nuzhat, Blick, Tony, Newgreen, Donald F., Thompson, Erik W., Ackland, M. Leigh
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2012
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343200/
https://ncbi.nlm.nih.gov/pubmed/22314376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12307-012-0098-7
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