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A mouse model of vitiligo with focused epidermal depigmentation requires IFN-γ for autoreactive CD8(+) T cell accumulation in the skin

Vitiligo is an autoimmune disease of the skin causing disfiguring patchy depigmentation of the epidermis and, less commonly, hair. Therapeutic options for vitiligo are limited, reflecting in part limited knowledge of disease pathogenesis. Existing mouse models of vitiligo consist of hair depigmentat...

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Detalhes bibliográficos
Main Authors: Harris, John E., Harris, Tajie H., Weninger, Wolfgang, Wherry, E. John, Hunter, Christopher A., Turka, Laurence A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343174/
https://ncbi.nlm.nih.gov/pubmed/22297636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2011.463
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