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Efficacy of Rho-Kinase Inhibitor Fasudil in Secondary Raynaud’s Phenomenon
OBJECTIVE: The RhoA/Rho-kinase pathway plays a pivotal role in cold induced vasoconstriction, vascular smooth muscle cells function and vascular homeostasis. This study evaluates the efficacy of fasudil, a RhoA/Rho-kinase inhibitor, to reverse cold-induced vasospasm in patients with Raynaud’s phenom...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3343172/ https://ncbi.nlm.nih.gov/pubmed/22275160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acr.21622 |
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