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Are Long-Range Structural Correlations Behind the Aggregration Phenomena of Polyglutamine Diseases?

We have characterized the conformational ensembles of polyglutamine [Image: see text] peptides of various lengths [Image: see text] (ranging from [Image: see text] to [Image: see text]), both with and without the presence of a C-terminal polyproline hexapeptide. For this, we used state-of-the-art mo...

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Detalhes bibliográficos
Main Authors: Moradi, Mahmoud, Babin, Volodymyr, Roland, Christopher, Sagui, Celeste
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343152/
https://ncbi.nlm.nih.gov/pubmed/22577357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002501
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