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Maternal Undernourished Fetal Kidneys Exhibit Differential Regulation of Nephrogenic Genes Including Downregulation of the Notch Signaling Pathway

Maternal undernutrition results in offspring nephron number reduction and hypertension that are hypothesized to begin as compensatory changes in fetal gene expression during gestation. To evaluate mechanisms of dysregulated nephrogenesis, pregnant Sprague Dawley rats were 50% food restricted from em...

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Detalhes bibliográficos
Main Authors: Magee, Thomas R., Tafti, Sanaz A., Desai, Mina, Liu, Qinghai, Ross, Michael G., Nast, Cynthia C
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343135/
https://ncbi.nlm.nih.gov/pubmed/21273641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719110393025
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