Microarray Analysis of LTR Retrotransposon Silencing Identifies Hdac1 as a Regulator of Retrotransposon Expression in Mouse Embryonic Stem Cells

Retrotransposons are highly prevalent in mammalian genomes due to their ability to amplify in pluripotent cells or developing germ cells. Host mechanisms that silence retrotransposons in germ cells and pluripotent cells are important for limiting the accumulation of the repetitive elements in the ge...

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Detalhes bibliográficos
Main Authors: Reichmann, Judith, Crichton, James H., Madej, Monika J., Taggart, Mary, Gautier, Philippe, Garcia-Perez, Jose Luis, Meehan, Richard R., Adams, Ian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343110/
https://ncbi.nlm.nih.gov/pubmed/22570599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002486
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