Macrophage Activation Associated with Chronic Murine Cytomegalovirus Infection Results in More Severe Experimental Choroidal Neovascularization

The neovascular (wet) form of age-related macular degeneration (AMD) leads to vision loss due to choroidal neovascularization (CNV). Since macrophages are important in CNV development, and cytomegalovirus (CMV)-specific IgG serum titers in patients with wet AMD are elevated, we hypothesized that chr...

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Bibliographic Details
Main Authors: Cousins, Scott W., Espinosa-Heidmann, Diego G., Miller, Daniel M., Pereira-Simon, Simone, Hernandez, Eleut P., Chien, Hsin, Meier-Jewett, Courtney, Dix, Richard D.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343109/
https://ncbi.nlm.nih.gov/pubmed/22570607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002671
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