Deconvolution of the Cellular Force-Generating Subsystems that Govern Cytokinesis Furrow Ingression

Cytokinesis occurs through the coordinated action of several biochemically-mediated stresses acting on the cytoskeleton. Here, we develop a computational model of cellular mechanics, and using a large number of experimentally measured biophysical parameters, we simulate cell division under a number...

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Bibliographic Details
Main Authors: Poirier, Christopher C., Ng, Win Pin, Robinson, Douglas N., Iglesias, Pablo A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343096/
https://ncbi.nlm.nih.gov/pubmed/22570593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002467
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