Common Variants at 9p21 and 8q22 Are Associated with Increased Susceptibility to Optic Nerve Degeneration in Glaucoma

Optic nerve degeneration caused by glaucoma is a leading cause of blindness worldwide. Patients affected by the normal-pressure form of glaucoma are more likely to harbor risk alleles for glaucoma-related optic nerve disease. We have performed a meta-analysis of two independent genome-wide associati...

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Main Authors: Wiggs, Janey L., Yaspan, Brian L., Hauser, Michael A., Kang, Jae H., Allingham, R. Rand, Olson, Lana M., Abdrabou, Wael, Fan, Bao J., Wang, Dan Y., Brodeur, Wendy, Budenz, Donald L., Caprioli, Joseph, Crenshaw, Andrew, Crooks, Kristy, DelBono, Elizabeth, Doheny, Kimberly F., Friedman, David S., Gaasterland, Douglas, Gaasterland, Terry, Laurie, Cathy, Lee, Richard K., Lichter, Paul R., Loomis, Stephanie, Liu, Yutao, Medeiros, Felipe A., McCarty, Cathy, Mirel, Daniel, Moroi, Sayoko E., Musch, David C., Realini, Anthony, Rozsa, Frank W., Schuman, Joel S., Scott, Kathleen, Singh, Kuldev, Stein, Joshua D., Trager, Edward H., VanVeldhuisen, Paul, Vollrath, Douglas, Wollstein, Gadi, Yoneyama, Sachiko, Zhang, Kang, Weinreb, Robert N., Ernst, Jason, Kellis, Manolis, Masuda, Tomohiro, Zack, Don, Richards, Julia E., Pericak-Vance, Margaret, Pasquale, Louis R., Haines, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343074/
https://ncbi.nlm.nih.gov/pubmed/22570617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002654
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