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Sequence-Specific Targeting of Dosage Compensation in Drosophila Favors an Active Chromatin Context
The Drosophila MSL complex mediates dosage compensation by increasing transcription of the single X chromosome in males approximately two-fold. This is accomplished through recognition of the X chromosome and subsequent acetylation of histone H4K16 on X-linked genes. Initial binding to the X is thou...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3343056/ https://ncbi.nlm.nih.gov/pubmed/22570616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002646 |
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