Myxoid Liposarcoma-Associated EWSR1-DDIT3 Selectively Represses Osteoblastic and Chondrocytic Transcription in Multipotent Mesenchymal Cells

BACKGROUND: Liposarcomas are the most common class of soft tissue sarcomas, and myxoid liposarcoma is the second most common liposarcoma. EWSR1-DDIT3 is a chimeric fusion protein generated by the myxoid liposarcoma-specific chromosomal translocation t(12;22)(q13;q12). Current studies indicate that m...

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Detalhes bibliográficos
Main Authors: Suzuki, Kayo, Matsui, Yoshito, Higashimoto, Mami, Kawaguchi, Yoshiharu, Seki, Shoji, Motomura, Hiraku, Hori, Takeshi, Yahara, Yasuhito, Kanamori, Masahiko, Kimura, Tomoatsu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343026/
https://ncbi.nlm.nih.gov/pubmed/22570737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036682
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