Upregulation of the Wnt Co-Receptor LRP6 Promotes Hepatocarcinogenesis and Enhances Cell Invasion

BACKGROUND: Activation of the Wnt/β-catenin signaling pathway plays a crucial role in hepatocellular carcinoma (HCC). Low-density lipoprotein (LDL) receptor-related protein-6 (LRP6) is one of the co-receptors of the Wnt/β-catenin pathway and forms a signaling complex with Wnt ligand and Frizzled rec...

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Detalhes bibliográficos
Principais autores: Tung, Edmund Kwok-Kwan, Wong, Betty Yin-Chi, Yau, Tai-On, Ng, Irene Oi-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343020/
https://ncbi.nlm.nih.gov/pubmed/22570728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036565
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