IL28B polymorphisms influence stage of fibrosis and spontaneous or interferon-induced viral clearance in thalassemia patients with hepatitis C virus infection

BACKGROUND: Polymorphisms in the interleukin-28B are important determinants in the spontaneous and drug-induced control of hepatitis C virus infection. DESIGN AND METHODS: We assessed the association of rs8099917 and rs12979860 polymorphisms with spontaneous viral clearance, severity of liver fibros...

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Main Authors: Di Marco, Vito, Bronte, Fabrizio, Calvaruso, Vincenza, Capra, Marcello, Borsellino, Zelia, Maggio, Aurelio, Renda, Maria Concetta, Pitrolo, Lorella, Lo Pinto, Maria Carmela, Rizzo, Michele, Fiorenza, Flavia, Gerardi, Calogera, Grimaudo, Stefania, Di Cristina, Antonietta, Levrero, Massimo, Craxì, Antonio
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2012
Subjects:
Original Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342968/
https://ncbi.nlm.nih.gov/pubmed/22180419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.050351
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