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Hydrolysis of oligoribonucleotides: influence of sequence and length.

The chemical stability of phosphodiester bonds of some oligoribonucleotides in the presence of a cofactor like polyvinylpyrolidine (PVP) is sequence dependent. It was found that pyrimidine-A (YA) and pyrimidine-C (YC) are especially susceptible to hydrolysis. The hydrolyzability of this same phospho...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Nucleic Acids Res
Kaituhi matua: Kierzek, R
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Oxford University Press 1992
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334286/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1408823/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.19.5073
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