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2B4 Utilizes ITAM-Containing Receptor Complexes to Initiate Intracellular Signaling and Cytolysis()
2B4 is a member of the SLAM receptor family capable of activating NK cell cytotoxicity in the context of EBV infection. SAP (SLAM Associated Protein) deficiency causes defective signaling downstream of SLAM family receptors and high susceptibility to EBV. 2B4 costimulates natural cytotoxicity recept...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3342820/ https://ncbi.nlm.nih.gov/pubmed/21439641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2011.02.008 |
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