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PLATELET-DERIVED GROWTH FACTOR-C (PDGF-C) ACTIVATION BY SERINE PROTEASES: IMPLICATIONS FOR BREAST CANCER PROGRESSION
The PDGF family members are potent mitogens for cells of mesenchymal origin and serve as important regulators of cell migration, survival, apoptosis, and transformation. Tumor-derived PDGF ligands are thought to function in both autocrine and paracrine manners, activating receptors on tumor and surr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3342761/ https://ncbi.nlm.nih.gov/pubmed/22035541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111020 |
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