Site-specific cleavage of IGF-II mRNAs requires sequence elements from two distinct regions of the IGF-II gene.

The human insulin-like growth factor II (IGF-II) gene constitutes a complex transcriptional unit that contains nine exons and four promoters. Expression of the IGF-II gene yields a family of mRNAs that all encode prepro-IGF-II. In addition, a stable 1.8 kb RNA is formed that is derived from the 3' u...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Meinsma, D, Scheper, W, Holthuizen, P E, Van den Brande, J L, Sussenbach, J S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1992
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334276/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1408818/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.19.5003
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