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Electronic Effects in the Pt-Catalyzed Cycloisomerization of Propargylic Esters: Synthesis of 2,3-Disubstituted Indolizines as a Mechanistic Probe

[Image: see text] The initial 5-exo versus 6-endo cyclization of the acyl group onto the activated alkyne of propargylic esters has been found to be dependent on electronic effects of the acyl, alkyne, and propargylic carbon substituents. These electronic effects control the ratio of 2,3-disubstitut...

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Detalhes bibliográficos
Main Authors: Hardin, Alison R., Sarpong, Richmond
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342703/
https://ncbi.nlm.nih.gov/pubmed/17845052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol701973s
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