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Epitope specificity is critical for high and moderate avidity cytotoxic T lymphocytes associated with control of viral load and clinical disease in horses with equine infectious anemia virus

Equine infectious anemia virus (EIAV) is a lentivirus that causes persistent infections in horses. We hypothesized that high-avidity CTL specific for nonvariable epitopes might be associated with low viral load and minimal disease in EIAV-infected horses. To test this hypothesis, memory CTL (CTLm) r...

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Bibliografiske detaljer
Main Authors: Mealey, Robert H., Zhang, Baoshan, Leib, Steven R., Littke, Matt H., McGuire, Travis C.
Format: Artigo
Sprog:Inglês
Udgivet: 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342690/
https://ncbi.nlm.nih.gov/pubmed/12954220
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