Early detection of dominant Env-specific and subdominant Gag-specific CD8+ lymphocytes in equine infectious anemia virus-infected horses using major histocompatibility complex class I/peptide tetrameric complexes

Cytotoxic T lymphocytes (CTL) are critical for control of lentiviruses, including equine infectious anemia virus (EIAV). Measurement of equine CTL responses has relied on chromium-release assays, which do not allow accurate quantitation. Recently, the equine MHC class I molecule 7-6, associated with...

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Autores principales: Mealey, Robert H., Sharif, Amin, Ellis, Shirley A., Littke, Matt H., Leib, Steven R., McGuire, Travis C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2005
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342685/
https://ncbi.nlm.nih.gov/pubmed/15979679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2005.05.025
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