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Metabolic Imbalance Associated with Methylation Dysregulation and Oxidative Damage in Children with Autism

Oxidative stress and abnormal DNA methylation have been implicated in the pathophysiology of autism. We investigated the dynamics of an integrated metabolic pathway essential for cellular antioxidant and methylation capacity in 68 children with autism, 54 age-matched control children and 40 unaffect...

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Autores principales: Melnyk, Stepan, Fuchs, George J., Schulz, Eldon, Lopez, Maya, Kahler, Stephen G., Fussell, Jill J., Bellando, Jayne, Pavliv, Oleksandra, Rose, Shannon, Seidel, Lisa, Gaylor, David W., James, S. Jill
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342663/
https://ncbi.nlm.nih.gov/pubmed/21519954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10803-011-1260-7
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