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Site-Selective Catalysis: towards a regiodivergent resolution of 1,2-diols

This paper demonstrates that the secondary hydroxyl can be functionalized in preference to the primary hydroxyl of a 1,2-diol. The site selectivity is achieved by using an enantioselective organic catalyst that is able to reversibly and covalently bond to the diol. The reaction was parlayed into a d...

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Detalhes bibliográficos
Main Authors: Worthy, Amanda D., Sun, Xixi, Tan, Kian L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342470/
https://ncbi.nlm.nih.gov/pubmed/22515351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3027086
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