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Non-synonymous variants in Pre B-cell leukemia homeobox (PBX) genes are associated with congenital heart defects

Congenital cardiac malformations are one of the most common birth defects and most are believed to be multigenic/multifactorial in nature. Recently mice lacking Pre-B cell leukemia transcription homeobox (PBX) genes were created and found to have a range of ventricular outflow tract (OFT) malformati...

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Detalhes bibliográficos
Main Authors: Arrington, Cammon B., Dowse, Benjamin R., Bleyl, Steven B., Bowles, Neil E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342453/
https://ncbi.nlm.nih.gov/pubmed/22426282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmg.2012.02.002
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