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Ethanol triggers sphingosine 1-phosphate elevation along with neuroapoptosis in the developing mouse brain

Our previous studies have indicated that de novo ceramide synthesis plays a critical role in ethanol-induced apoptotic neurodegeneration in the 7-day-old mouse brain. Here, we examined whether the formation of sphingosine 1-phosphate (S1P), a ceramide metabolite, is associated with this apoptotic pa...

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Detalhes bibliográficos
Main Authors: Chakraborty, Goutam, Saito, Mitsuo, Shah, Relish, Mao, Rui-Fen, Vadasz, Csaba, Saito, Mariko
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342397/
https://ncbi.nlm.nih.gov/pubmed/22393932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07723.x
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