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The Role of Heat Shock Proteins in Antigen Cross Presentation

Heat shock proteins (HSPs) are molecular chaperones that bind tumor antigens and mediate their uptake into antigen presenting cells. HSP–antigen complexes are then directed toward either the MHC class I pathway through antigen cross presentation or the conventional class II pathway, leading to activ...

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Autors principals: Murshid, Ayesha, Gong, Jianlin, Calderwood, Stuart K.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342350/
https://ncbi.nlm.nih.gov/pubmed/22566944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00063
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