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Inflammation and Bone Destruction in Arthritis: Synergistic Activity of Immune and Mesenchymal Cells in Joints

Rheumatoid arthritis (RA) is an immune-mediated disease of the joints that is characterized by chronic inflammation and synovial hyperplasia that eventually lead to cartilage and bone destruction. Synovial fibroblasts are mesenchymal cells recognized as a key cell population in RA due to their hyper...

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Detalhes bibliográficos
Main Authors: Komatsu, Noriko, Takayanagi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342288/
https://ncbi.nlm.nih.gov/pubmed/22566958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00077
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