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Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors

IMPORTANCE OF THE FIELD: Axl and/or Mer expression correlates with poor prognosis in several cancers. Until recently, the specific role of these receptor tyrosine kinases (RTKs) in the development and progression of cancer remained unexplained. Studies demonstrating that Axl and Mer contribute to me...

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Hlavní autoři: Linger, Rachel M.A., Keating, Amy K., Earp, H. Shelton, Graham, Douglas K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342018/
https://ncbi.nlm.nih.gov/pubmed/20809868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2010.515980
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